Big Anti-Aging Hit

Hydrogen's Size Allows Cell Transformations

Big Anti-Aging Hit. Healthy Living Magazine

Big Anti-Aging Hit. Healthy Living Magazine

Because of its size, molecular hydrogen can do a lot of things larger molecules of known antioxidants can’t. Molecular hydrogen affects all cells of the body, crosses the blood-brain barrier and can move readily into the cell energy factories (mitochondria); it “even has the ability to translocate to the nucleus under certain conditions,” reports Dr Brandon J Dixon in Medical Gas Research.

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Once in these ideal locations of the cell, molecular hydrogen’s effects are documented as being an antioxidant, anti-inflammatory and influencing the genetics of cell life.

Studies conducted since 2007 find molecular hydrogen’s use in health could change the physiological fate of at least 183.6 million Americans—and what’s more its effects can be obtained with a dietary supplement.

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Studies show people with diabetes, arthritis, heart disease and high cholesterol who consume extra amounts of molecular hydrogen experience lower blood sugar, inflammation, cholesterol and higher antioxidant activity. Molecular hydrogen could also find its place in sports performance, age-related dementia and Parkinson’s disease.

How this one molecule affects so many different systems and organs is a question researchers have been examining ever since the seminal molecular hydrogen in health medicine article came out in Nature Medicine in 2007.

therapeutic gas

More than 400 scientific studies, including 30-plus human clinical evaluations, most conducted in the last seven years, find molecular hydrogen effective in seemingly every organ of the body and in 140 human disease models, says the Molecular Hydrogen Research Foundation.

aging diseases and hydrogen

The human studies have focused, in particular, on diabetics. These participants went into their trials with high blood sugar, blood pressure, cholesterol levels, inflammation, obesity and insulin resistance, all hallmarks of aging diseases. Known as Syndrome X or metabolic disease, one in three adults in the US experience these symptoms.

In 2008 researchers looked at the effect of supplementing molecular hydrogen in diabetics and others with poor sugar control. The main cause of aging among diabetics especially is oxidative stress, caused by free radicals whose elevated production is linked with pre-disease states.

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The study investigated the effects of H2 intake on cholesterol and sugar levels in 30 patients with either type 2 diabetes mellitus (T2DM) or impaired glucose tolerance (IGT). The patients consumed either pressurized hydrogen-rich pure water or 900 mL of placebo pure water for 8 weeks with a 12-week washout period. Patients in the hydrogen water group experienced “decreases in the levels of modified lowdensity lipoprotein (LDL) cholesterol… small dense LDL and urinary 8-isoprostanes.”

cholesterol and weight loss

Hydrogen intake decreased serum concentrations of oxidized LDLs, the kind of cholesterol linked with artery and heart disease. Levels of the fat-burning hormone adiponectin (that aids weight loss) and superoxide dismutase (SOD), one of the body’s primary antioxidants, went up.

diet replacement

In 4 of 6 patients with IGT, hydrogen “normalized” oral glucose tolerance tests.

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Long-term intake of hydrogen “controlled fat and body weights despite no change in the consumption of food and water” and decreased blood sugar, insulin and triglycerides, the effect of which was similar to diet restriction, according to an independently confirming study. Gene expression in the liver was enhanced and expressed as the protein-based fibroblast growth factor 21 “which should function to enhance fatty acid and glucose expenditure. These results suggest the potential benefit of H2 in treating obesity, diabetes and metabolic syndrome.”

hydrogen delivery

The difficulty of delivering hydrogenenriched water is that it can only hold about 1.6 ppm of H2 unless pressurized. However H2 can also be produced via a dietary supplement and delivered to the tissues through the interaction of specific types of magnesium, malic acid and hydrogen bound in water. A molecular hydrogen dietary supplement can be taken daily. One supplement delivers three types of magnesium with micro-encapsulated malic and fumaric acids and 74 bioavailable coral minerals. As the capsule ingredients react, millions of tiny H2 bubbles saturate the body’s cells to raise mitochondrial (energy) and antioxidant activity, especially SOD and glutathione, as well as positively influence cell signalling and gene expression. These anti-aging effects may increase one’s overall state of health, say anti-aging physicians such as Julian Whitaker, MD who’s begun to recommend molecular hydrogen to patients as a daily supplement.

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ReferencesAbrous DN, Koehl M, Le Moal M. Adult neurogenesis: from precursors to network and physiology. Physiol Rev. 2005;85:523– 569. [PubMed] Aoki K, Nakao A, Adachi T, Matsui Y, Miyakawa S. Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Med Gas Res. 2012 Jul 12;2:12. doi: 10.1186/2045-9912-2-12. eCollection 2012. Dixon BJ, Tang J, Zhang JH. The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance. Med Gas Res. 2013; 3: 10. Published online 2013 May 16. doi: 10.1186/2045-9912-3-10PMCID: PMC3660246 Fujita K, Seike T, Yutsudo N, et al. Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine mouse model of Parkinson’s disease. PLoS One. 2009;4:e7247. [PMC free article][PubMed] Fu Y, Ito M, Fujita Y, et al. Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson’s disease. Neurosci Lett. 2009;453:81–55. [PubMed] Ishibashi T, Sato B, Rikitake M, Seo T, Kurokawa R, Hara Y, Naritomi Y, Hara H, Nagao T. Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med Gas Res. 2012 Oct 2;2(1):27. doi: 10.1186/2045-9912-2-27. Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M, Adachi T, Obayashi H, Yoshikawa T. Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr Res. 2008 Mar;28(3):137-43. doi: 10.1016/j.nutres.2008.01.008. Kamimura N, Nishimaki K, Ohsawa I, Ohta S. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice. Obesity (Silver Spring) 2011 in press. [PubMed] Nagata K, Nakashima-Kamimura N, Mikami T, Ohsawa I, Ohta S. Consumption of molecular hydrogen prevents the stress-induced impairments in hippocampus-dependent learning tasks during chronic physical restraint in mice. Prog Neuropsychopharmacol. 2009;34:501–508. [PubMed] Nakao A, Toyoda Y, Sharma P, Evans M, Guthrie N. Effectiveness of hydrogen rich water on antioxidant status of subjects with potential metabolic syndrome-an open label pilot study. J Clin Biochem Nutr. 2010 Mar;46(2):140-149. doi: 10.3164/jcbn.09-100. E-pub 2010 Feb 24. Oharazawa H, Igarashi T, Yokota T, et al. Protection of the retina by rapid diffusion of hydrogen: administration of hydrogenloaded eye drops in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci. 2010;51:487–492. Ohsawa I, Ishikawa M, Takahashi K, Watanabe M, Nishimaki K, Yamagata K, Katsura K, Katayama Y, Asoh S, Ohta S. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med 2007, 13:688-694. PubMed Abstract | Publisher Full Text
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