Liver's Bodyguard

Modern, Enhanced Garlic

Liver's Bodyguard, Healthy Living Magazine, Anti-aging

Liver's Bodyguard, Healthy Living Magazine, Anti-aging

Garlic, a versatile protectant for controlling high blood pressure as well as fighting cancer and diseases, is being used without its natural limitations in a modern enhanced form of Aged Garlic Extract.

People should never take their liver and what it does for the human body for granted. Nor should one abuse this organ intentionally, since our polluted environment heaps enough toxicity on it without our piling on the harmful effects with willful intent such as imbibing alcohol or using street drugs. Without a normally functioning liver, one wouldn’t be able to detoxify poisonous chemicals, stockpile vitamins and minerals, convert food to stored energy, manufacture blood, bile and proteins or metabolize cholesterol and hormones.

Therefore, an overburdened liver can result in toxic overload, poor food utilization, chronic fatigue, overweight, water retention, hypoglycemia, hyperthyroidism and high cholesterol. Not to mention specific diseases such as fatty liver, hepatitis, cirrhosis and cancer.

Read: Anti-Aging Boost
From Garlic's Chemicals

According to the American Liver Foundation, about one in 10 Americans are or have been afflicted with liver and biliary (bile duct) diseases. Nearly one third of American adults in a large urban population sample had fatty liver disease and 80% had normal blood tests. Subclinical liver disease that flies below the radar is common.

At risk of developing liver disease are people who have a family history; are obese; eat a high-fat, high-cholesterol diet; drink alcohol; take multiple over-the-counter or prescription drugs; use street drugs; have unprotected sex with multiple partners; or who had a blood transfusion before July 1992. (Some liver diseases are caused by stress to the liver in the form of diet, alcohol and drugs. Others are contagious. Hepatitis B and C, for example, can both be transmitted through blood. Since July 1992, the US blood supply has routinely been screened for these viruses.)

Yet because of our toxic society, everyone is vulnerable to developing liver problems. Every day our liver has to deal with food additives, pesticides, hormones and antibiotics in meats, heavy metals in fish, fumes from cars and chlorine in water.

Subclinical Disease Victims

The September 2013 issue of the Journal of Clinical Biochemistry and Nutrition reported from the Graduate School of Medicine, Osaka City University, Japan, that S-allyl cysteine, one of the measured ingredients in a supplement called Aged Garlic Extract (AGE), attacks fatty liver disease at the genetic level to change enzyme expression.

Read: Garlic Smells Youth
Rich in antioxidants that fight free radicals, our biological enemies

While fresh garlic is too harsh on the stomach and leads to upset, cooking can destroy some of its most valuable compounds while not eliminating its fragrance.

The highly standardized odorless AGE is produced by long extraction and aging of organic fresh garlic at room temperature. The process increases antioxidant levels well above those of the fresh bulb and converts harsh unstable compounds, such as allicin, to stable health-promoting substances. AGE contains mostly stable, water-soluble organosulfur compounds, which are antioxidants. They include S-allyl mercaptocysteine, a compound unique to AGE and S-allyl cysteine (SAC)—the standardized compound which is highly bioavailable at a 98% absorption rate. AGE is processed for some 20 months following its harvest in an aqueous ethanol solution in stainless steel tanks; this brings out garlic’s antioxidants and sulfur compounds, yet eliminates the native not so pleasant aroma we don’t want. In addition to well documented effects on blood pressure and cancer prevention, AGE is building up scientific credibility in the field of liver disease and diabetes, especially as it increases cell production of glutathione that is needed for drug detoxification, including from commonly used painkillers containing acetaminophen.

Seeking to prevent complications of diabetes, of which fatty liver disease is one, the scientists in the most recent study noted the antioxidant activity of AGE. In rats with nonalcoholic fatty liver disease, S-allyl cysteine put blood sugar back into normal range and lowered triglycerides and low-density lipoprotein cholesterol levels, all because of improved liver enzyme function. “In conclusion, these findings support the hypothesis that S-allyl cysteine has diabetic and nonalcoholic fatty liver disease therapeutic potential as a potent regulating agent against lipogenesis and glucose metabolism.”

But, then, when haven’t scientists known AGE as the liver’s bodyguard? In 1985 in the Hiroshima Journal of Medicine Science (34;3:303-309) S-allyl cysteine was said to have suppressed the cell damaging activity of carbon tetrachloride. AGE was also shown in 1998 in Toxicology (126;3:213-222) to protect liver cells from the sedative drug phenobarbitol with a toxic industrial solvent, a sublethal combination with effects worse than alcohol. The scarring of the liver by these chemical solvents causes fibrosis or hardening of the liver. An earlier study from the Osaka City University in Japan illuminates the compound’s protective mechanism of action.

Liver scarring, known as hepatic fibrosis, is the progressive pathology of many liver diseases. In this study of rats with porcine-induced liver fibrosis or scarring, orally administered AGE “markedly attenuated the development of hepatic fibrosis” and “could provide a new therapeutic strategy for hepatic fibrosis.” Researchers reported in FASEB Journal (1993;7:A864) that AGE increased activity of detoxification and antioxidant enzymes in the liver. The liver produces superoxide dismutase, catalase and glutathione peroxidase, antioxidants that scavenge free radical injuring cells. Researchers say in Nutrition Research (1998;18:1[61- 70]) that AGE raises activity of all three. These antioxidants minimize the fibrotic effects of chemical toxins. A dietary supplement with Aged Garlic Extract processed as detailed in this artricle can be purchased over the counter in various combinations to address heart, circulatory, cholesterol and immune function as well as cancer protection.

American Liver Foundation:
Browning, JD. et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity. Hepatology, Dec 2004;40:6;1387-1395.
Shinkawa H, Takemura S, Minamiyama Y, Kodai S, Tsukioka T, Osada-Oka M, Kubo S, Okada S, Suehiro S. S-allylcysteine is effective as a chemopreventive agent against porcine serum-induced hepatic fibrosis in rats. Osaka City Med J. 2009 Dec;55(2):61-69.
Takemura S, Minamiyama Y, Kodai S, Shinkawa H, Tsukioka T, Okada S, Azuma H, Kubo S. S-Allyl cysteine improves nonalcoholic fatty liver disease in type 2 diabetes Otsuka Long-Evans Tokushima Fatty rats via regulation of hepatic lipogenesis and glucose metabolism. J Clin Biochem Nutr. 2013 Sept;53(2):94-101. doi: 10.3164/jcbn.13-1. E-pub 2013 Aug 31.
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